Chen Junhong, Cao Tiesheng, Duan Yunyou, Yuan Lijun, Yang Yong
Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, No. 1 Xinsi Road, Baqiao District, Xi'an, Shann'xi Province 710038, China.
Echocardiography. 2007 Oct;24(9):940-5. doi: 10.1111/j.1540-8175.2007.00492.x.
To assess the regional systolic function in patients with post myocardial infarction (PMI), using the velocity vector imaging (VVI) technique, a new two-dimensional echocardiographic method.
Two-dimensional images of apical four, two chambers and apical long-axis view were obtained in 20 patients with PMI and 15 normal controls. The segmental myocardial systolic peak strain (epsilon), strain rate (SRs), and segmental ejection fraction (SEF) were analyzed with VVI offline software. The result of epsilon in middle segments of the normal control analyzed by VVI was compared with that by tissue Doppler imaging (DTI).
The segmental epsilon, SRs, and SEF were significantly lower in infarct segments than in the corresponding segments of the normal controls. There were significant difference in average epsilon, SRs, and SEF among infarct, noninfarct, and normal control segments. The segmental epsilon, SRs, and SEF did not vary significantly from basal to apical segments in the normal control subjects. There was a good correlation on epsilon in middle segments between VVI and DTI (r = 0.710, P < 0.01). The interobserver variability was 4.6% and the intraobserver variability was 7.0%, respectively.
The regional systolic function decreased in infarct segments compared with the adjacent noninfarct segments and normal control segments. The systolic function of adjacent noninfarct area was also affected by infarct areas. VVI could recognize and quantify the abnormality of infarct segments and therefore could be a useful tool in assessing the myocardial regional systolic function.
采用一种新的二维超声心动图方法——速度向量成像（VVI）技术，评估心肌梗死后（PMI）患者的局部收缩功能。
获取20例PMI患者和15例正常对照者的心尖四腔、两腔和心尖长轴观二维图像。使用VVI离线软件分析节段性心肌收缩期峰值应变（ε）、应变率（SRs）和节段性射血分数（SEF）。将VVI分析的正常对照者中间节段的ε结果与组织多普勒成像（DTI）分析的结果进行比较。
梗死节段的节段性ε、SRs和SEF显著低于正常对照者的相应节段。梗死节段、非梗死节段和正常对照节段之间的平均ε、SRs和SEF存在显著差异。正常对照者从基底部到心尖部节段的节段性ε、SRs和SEF无显著变化。VVI与DTI在中间节段的ε上具有良好的相关性（r = 0.710，P < 0.01）。观察者间变异性分别为4.6%，观察者内变异性为7.0%。
与相邻的非梗死节段和正常对照节段相比，梗死节段的局部收缩功能降低。梗死区域也影响相邻非梗死区域的收缩功能。VVI能够识别并量化梗死节段的异常，因此可能是评估心肌局部收缩功能的有用工具。
