[Effect of arterio-venous fistula blood flow dynamics on ECG abnormalities in chronic hemodialysis patients].

UNLABELLED

The dialysis doses is mostly dependent on well functional permanent vascular access. From the other hand high vascular access blood flow (Qva) may induce cardiac problems in HD patients. The purpose of this study was to investigate the effect of vascular access dynamics on electrocardiographic abnormalities in hemodialysis patients. Therefore, forty non-diabetic, HD patients, with native vascular access (VA) were divided into two equal groups; with Qva > 1500 ml/min (group A), and also Qva < 1500 ml/min (group B). The average of VA survival period was 28 +/- 18 (mean +/- SE) (group A), and 29 +/- 15 (months) (group B). The Qva measurements monitoring by color Doppler sonography included also: maximal velocity (Vmax), time average of maximal velocity (TAMX), pulsate index (PI), and resistive index (RI). Kt/V index was calculated, as classical parameter of adequacy, and also shunt recirculation using 3 urea samples was measured. For estimation of cardiac function we used M-mode echocardiography, and 24-hours ECG (Holter) monitoring. The occurrence of ventricular (VE), and supraventricular extrasystoles (SVE), ST-T, and ST characteristic as well were monitored by 24-hours Holter.

CONCLUSIONS

1. In the group with high Qva (A) we observed significantly higher number of VE, and also of SVE recorded by Holter monitoring compared with the low Qva group (B). 2. The mean number of patients with ST-T changes was higher in group A (12 vs. 7), but number of patients with recorded by Holter ST depression, and ST elevation between investigated groups were similar. 3. The mean number of ventricular arrhythmias of Lown classified as 4A, and 4B of Lown grading was significantly higher in the group with high Qva (A).