双相情感障碍谱系障碍筛查工具的开发与验证：心境障碍问卷
Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire.
作者信息
Hirschfeld R M, Williams J B, Spitzer R L, Calabrese J R, Flynn L, Keck P E, Lewis L, McElroy S L, Post R M, Rapport D J, Russell J M, Sachs G S, Zajecka J
机构信息
Department of Psychiatry and Behavioral Sciences, Medical Branch, the University of Texas at Galveston 77555-01888, USA.
出版信息
Am J Psychiatry. 2000 Nov;157(11):1873-5. doi: 10.1176/appi.ajp.157.11.1873.
OBJECTIVE
Bipolar spectrum disorders, which include bipolar I, bipolar II, and bipolar disorder not otherwise specified, frequently go unrecognized, undiagnosed, and untreated. This report describes the validation of a new brief self-report screening instrument for bipolar spectrum disorders called the Mood Disorder Questionnaire.
METHOD
A total of 198 patients attending five outpatient clinics that primarily treat patients with mood disorders completed the Mood Disorder Questionnaire. A research professional, blind to the Mood Disorder Questionnaire results, conducted a telephone research diagnostic interview by means of the bipolar module of the Structured Clinical Interview for DSM-IV.
RESULTS
A Mood Disorder Questionnaire screening score of 7 or more items yielded good sensitivity (0.73) and very good specificity (0.90).
CONCLUSIONS
The Mood Disorder Questionnaire is a useful screening instrument for bipolar spectrum disorder in a psychiatric outpatient population.
目的
双相谱系障碍包括双相I型、双相II型及未另行规定的双相障碍，常常未被识别、诊断及治疗。本报告描述了一种名为心境障碍问卷的新型双相谱系障碍简短自评筛查工具的验证情况。
方法
共有198名在五家主要治疗心境障碍患者的门诊就诊的患者完成了心境障碍问卷。一名对心境障碍问卷结果不知情的研究专业人员通过《精神疾病诊断与统计手册》第四版（DSM-IV）结构化临床访谈的双相模块进行了电话研究诊断访谈。
结果
心境障碍问卷筛查分数为7项及以上时，具有良好的敏感性（0.73）和非常好的特异性（0.90）。
结论
心境障碍问卷是一种用于精神科门诊人群双相谱系障碍的有用筛查工具。
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