Stephens G M, Raboud J M, Karakas L, Sherlock C H
Diagnostic Virology and Reference Laboratory, University of British Columbia, Vancouver, British Columbia, Canada.
J Clin Microbiol. 2000 Nov;38(11):4264-5. doi: 10.1128/JCM.38.11.4264-4265.2000.
Two hepatitis C antibody assays were used to test diluted positive sera. Dilutions of 1 in 5, 1 in 10, and 1 in 20 all resulted in loss of reactivity, with the greatest losses occurring in samples with low and moderate reactivities. These results disqualify pooling as a strategy for seroprevalence studies and screening programs.
使用两种丙型肝炎抗体检测方法对稀释后的阳性血清进行检测。1:5、1:10和1:20的稀释度均导致反应性丧失，反应性低和中等的样本丧失最为明显。这些结果表明，混合检测不适用于血清流行率研究和筛查项目。
