Lai S, Chen J, Celentano D, Page J B, Lai H, Yang J, Liu W, McCoy C B, Yu X F
Comprehensive Drug Research Center, Department of Medicine, University of Miami School of Medicine, Florida, USA.
J Psychoactive Drugs. 2000 Jul-Sep;32(3):285-92. doi: 10.1080/02791072.2000.10400451.
This preliminary study collected data from 326 heroin users in Guangxi Province, China, in 1997. Logistic regression analysis was performed to identify the risk factors for injection. Survival analysis identified factors independently associated with time from initiation of heroin use to adoption of injection. Four factors were independently associated with injection: number of friends who used heroin in the last year, duration of heroin use, dose of heroin consumed, and total number of times detoxified in drug treatment and rehabilitation centers. Only gender and duration of heroin use were independently associated with time to first injection. Median time to first injection was 11 months for males and 22 months for females. Median time to first injection varied by age. Median time to injection for those who used heroin for more than one year was 8.1 months; it was 19.1 months for on to five years of use, and 40.5 months for more than five years of use. This study's preliminary findings suggest that younger, more recent heroin users, and males are at increased risk of becoming injectors, a major risk behavior for HIV acquisition.
这项初步研究于1997年在中国广西收集了326名海洛因使用者的数据。进行了逻辑回归分析以确定注射的风险因素。生存分析确定了与从开始使用海洛因到采用注射方式的时间独立相关的因素。有四个因素与注射独立相关:去年使用海洛因的朋友数量、海洛因使用时长、海洛因消费量以及在戒毒治疗和康复中心戒毒的总次数。只有性别和海洛因使用时长与首次注射时间独立相关。男性首次注射的中位时间为11个月,女性为22个月。首次注射的中位时间因年龄而异。使用海洛因超过一年者首次注射的中位时间为8.1个月;使用一至五年者为19.1个月,使用超过五年者为40.5个月。该研究的初步结果表明,更年轻、刚开始使用海洛因的使用者以及男性成为注射者的风险增加,而注射是感染艾滋病毒的一种主要风险行为。