Department of Nursing, National Cheng Kung University Hospital, Tainan, Taiwan.
Subst Use Misuse. 2011;46(5):591-8. doi: 10.3109/10826084.2010.526798. Epub 2010 Oct 21.
The purpose of the study was to determine heroin dependence and risky behaviors associated with human immunodeficiency virus (HIV) infection among newly incarcerated injection drug users (IDUs). Three self-administrated questionnaires were collected among 450 newly incarcerated male heroin users during 2005-2007. Inmates were categorized as heroin-dependent if they met three or more of the six ICD-10 criteria. Heroin-dependent inmates had higher scores of bloodborne virus transmission risk than non-dependent IDUs (12.8 ± 16.0 vs. 7.2 ± 11.5, p < 0.001). Multiple logistic regression analysis indicated that heroin dependence was a significant moderator of the association between risky injection behaviors and HIV infection. It is crucial to integrate substance treatment with behavioral interventions into harm reduction programs to prevent bloodborne virus transmission among IDUs.
本研究旨在确定新收监的注射吸毒者（IDU）中与人类免疫缺陷病毒（HIV）感染相关的海洛因依赖和危险行为。在 2005-2007 年间，我们对 450 名新收监的男性海洛因使用者进行了三次自我管理问卷调查。如果满足 ICD-10 标准中的三个或更多标准，则将被认定为海洛因依赖。与非依赖 IDU 相比，海洛因依赖者的血源性病毒传播风险评分更高（12.8 ± 16.0 对 7.2 ± 11.5，p<0.001）。多因素逻辑回归分析表明，海洛因依赖是危险注射行为与 HIV 感染之间关联的一个显著调节因素。将物质治疗与行为干预相结合纳入减少伤害计划，对于防止 IDU 中血源性病毒传播至关重要。
