Cohen G M, Nettleman M D
Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA.
Pediatrics. 2000 Nov;106(5):973-6. doi: 10.1542/peds.106.5.973.
The economic impact of routine vaccination of preschool children with inactivated influenza vaccine was investigated.
A decision analysis was performed using data from the literature. Direct and indirect costs of each vaccination strategy were calculated and compared with a strategy of not vaccinating.
Two settings were evaluated: a setting in which vaccination was available during flexible hours and a setting in which vaccination was available only during usual work hours (8:00 am-5:00 pm).
Vaccination resulted in a net cost savings in both settings. The net savings per vaccine recipient were $21.28 in the flexible setting and $1.20 in the restricted setting. Although the analysis was performed for the inactivated vaccine, sensitivity analysis showed that the nasal vaccine could also result in a net cost savings depending on the price of the cold-adapted vaccine when it is licensed.
Vaccinating preschool children is economically advantageous. Serious consideration should be given to recommending vaccination in this age group.
研究对学龄前儿童常规接种灭活流感疫苗的经济影响。
利用文献数据进行决策分析。计算每种疫苗接种策略的直接和间接成本,并与不接种疫苗的策略进行比较。
评估了两种情况:一种是在灵活时间内可接种疫苗的情况,另一种是仅在正常工作时间(上午8:00至下午5:00)可接种疫苗的情况。
在两种情况下,接种疫苗均带来了净成本节约。在灵活接种情况下,每位疫苗接种者的净节约为21.28美元,在受限接种情况下为1.20美元。尽管该分析是针对灭活疫苗进行的,但敏感性分析表明,根据冷适应疫苗获批后的价格,鼻用疫苗也可能带来净成本节约。
对学龄前儿童进行疫苗接种在经济上具有优势。应认真考虑在该年龄组推荐接种疫苗。