Gallego N, Estepa R, Mampaso F, García-S F, Reche A, Ortuño J
Department of Nephrology, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, Spain.
J Nephrol. 2000 Sep-Oct;13(5):373-6.
We describe a case of a 10 year-old boy who had fever, weakness, anorexia, weight loss and general malaise. No other remarkable symptoms were present. He had been treated with Aspirin and Ibuprofen. Deterioration of renal function, glucosuria, proteinuria, anemia and increased erythrocyte sedimentation rate were detected. After 7 days observation with no treatment, renal function worsened, glucosuria increased and fever persisted. A renal biopsy was performed and acute tubulointerstitial nephritis was diagnosed. The most common aetiologies of this entity were excluded. An ophthalmologic study revealed bilateral anterior uveitis, therefore the patient was diagnosed as having tubulointerstitial nephritis with uveitis. The child improved on corticosteroid therapy, but uveitis relapsed when treatment was stopped.
我们描述了一名10岁男孩的病例，他有发热、乏力、厌食、体重减轻和全身不适。没有其他明显症状。他曾接受阿司匹林和布洛芬治疗。检测到肾功能恶化、糖尿、蛋白尿、贫血和红细胞沉降率升高。未经治疗观察7天后，肾功能恶化，糖尿增加，发热持续。进行了肾活检，诊断为急性肾小管间质性肾炎。排除了该疾病最常见的病因。眼科检查显示双侧前葡萄膜炎，因此该患者被诊断为伴有葡萄膜炎的肾小管间质性肾炎。患儿接受皮质类固醇治疗后病情好转，但停药后葡萄膜炎复发。
