Ben Hamida F, Kheder M A, el Younsi F, Abderrahim E, Ben Moussa F, Goucha R, Ben Maiz H
Service de néphrologie et de médecine interne, Hôpital Charles Nicolle, Tunis.
Nephrologie. 1995;16(4):333-6.
The association of acute interstitial nephritis and uveitis is rare. In 1975, Dobrin reported a new syndrome in two children presenting acute interstitial nephritis, anterior uveitis and marrow-lymph node granulomas. We report one case of this association in the adult. A 35-year-old man was admitted to the hospital for acute renal failure, arthralgia and anterior uveitis. The infectious and the immunological investigations were negative. The ocular examination shows bilateral anterior uveitis. The renal biopsy revealed acute tubulo-interstitial nephritis. He was treated by prednisone (0.5 mg/Kg/day). His clinical course was favorable. Seven years later, the renal function is normal and we not observed a relapse of his uveitis.
急性间质性肾炎与葡萄膜炎的关联较为罕见。1975年,多布林报告了两例患有急性间质性肾炎、前葡萄膜炎和骨髓-淋巴结肉芽肿的儿童的一种新综合征。我们报告了一例成人的这种关联病例。一名35岁男性因急性肾衰竭、关节痛和前葡萄膜炎入院。感染和免疫学检查均为阴性。眼部检查显示双侧前葡萄膜炎。肾活检显示急性肾小管间质性肾炎。他接受了泼尼松(0.5毫克/千克/天)治疗。他的临床过程良好。七年后,肾功能正常,我们未观察到他的葡萄膜炎复发。