Ogane K, Fujita S, Ohkuma H, Suzuki S
Department of Neurosurgery, Hirosaki University School of Medicine, Hirosaki, Japan.
No To Shinkei. 2000 Sep;52(9):827-31.
We report a case of delayed subarachnoid hemorrhage (SAH) from a vertebrobasilar artery dissecting aneurysm (VBA-DA). The patient was a healthy 32-year-old woman with a sudden onset of severe occipitalgia. Next day, her headache improved gradually, and she consulted with our department. Although we initially suspected that she was suffering from SAH, neurological findings, CT, and cerebrospinal fluid examination did not reveal any abnormal conditions, including SAH. Therefore, she was treated conservatively with analgesics. Twelve days after the initial onset of the headache, she was admitted because of severe re-attack of headache, rt. hemiparesis with rt. oculomotor nerve palsy and loss of consciousness. CT revealed moderate SAH and cerebral angiograms showed VBA-DA. After the cerebral angiography, bleeding reoccurred two times and she lost her life. We present the case, review the literature and discuss the relationship between presenting symptom of headache and non-hemorrhagic VBA-DA. A few cases of non-hemorrhagic VBA-DA have been reported in the literature in which the only presenting symptom was headache, followed by delayed SAH from non-hemorrhagic dissecting aneurysm. Consequently, we concluded that her initial symptom of headache was due to dissection of vertebrobasilar artery, and that SAH was due to delayed hemorrhage of non-hemorrhagic VBA-DA. Even when neurological findings, CT and cerebrospinal fluid examination reveal no abnormalities in the early stage after the sudden onset of headache, especially in the occiptal or nuchal regions, non-hemorrhagic VBA-DA, which has a risk of fatal hemorrhage, cannot be ruled out with certainty. Therefore, MRI, MRA, three-dimensional CT, or cerebral angiography should be performed in such cases.
我们报告一例由椎基底动脉夹层动脉瘤(VBA-DA)导致的迟发性蛛网膜下腔出血(SAH)病例。患者为一名32岁健康女性,突然出现严重枕部疼痛。次日,她的头痛逐渐缓解,并前来我科就诊。尽管我们最初怀疑她患有SAH,但神经系统检查结果、CT及脑脊液检查均未发现任何异常情况,包括SAH。因此,给予她镇痛药进行保守治疗。头痛首发12天后,她因头痛再次剧烈发作、右侧偏瘫伴右侧动眼神经麻痹及意识丧失而入院。CT显示中度SAH,脑血管造影显示为VBA-DA。脑血管造影后,出血再次发生两次,患者最终死亡。我们呈现该病例,回顾相关文献,并讨论头痛的首发症状与非出血性VBA-DA之间的关系。文献中报道了少数几例非出血性VBA-DA病例,其唯一的首发症状为头痛,随后发生非出血性夹层动脉瘤导致的迟发性SAH。因此,我们得出结论,她最初的头痛症状是由于椎基底动脉夹层所致,而SAH是由于非出血性VBA-DA的迟发性出血。即使在头痛突然发作后的早期,神经系统检查结果、CT及脑脊液检查均未发现异常,尤其是在枕部或颈部区域,也不能完全排除有致命出血风险的非出血性VBA-DA。因此,在这种情况下应进行MRI、MRA、三维CT或脑血管造影检查。