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Clinical trial of the oral form of a new podophyllotoxin derivative, VP-16-213 (NSC-141540), in patients with advanced neoplastic disease.

作者信息

Nissen N I, Hansen H H, Pedersen H, Stroyer I, Dombernowsky P, Hessellund M

出版信息

Cancer Chemother Rep. 1975 Sep-Oct;59(5):1027-9.

PMID:1106845
Abstract
摘要

相似文献

1
Clinical trial of the oral form of a new podophyllotoxin derivative, VP-16-213 (NSC-141540), in patients with advanced neoplastic disease.新型鬼臼毒素衍生物VP-16-213(NSC-141540)口服制剂用于晚期肿瘤疾病患者的临床试验。
Cancer Chemother Rep. 1975 Sep-Oct;59(5):1027-9.
2
Phase I trial of a new form of an oral administration of VP-16-213.新型口服VP-16-213的I期试验
Cancer Treat Rep. 1979 Mar;63(3):485-7.
3
Clinical study of the new podophyllotoxin derivative, 4'-demethylepipodophyllotoxin 9-(4,6-o-ethylidene- beta-D-glucopyranoside) (NSC-141540; VP-16-213), in solid tumors.
Cancer Chemother Rep. 1975 Jul-Aug;59(4):737-42.
4
4'-demethylepipodophyllotoxin 9-(4,6-o-2-thenylidene-beta-D-glucopyranoside) (NSC-122819; VM-26) and 4'-demethylepipodophyllotoxin 9-(4.6-0-ethylidene-beta-D-glucopyranoside) (NSC-141540; VP-16-213) in childhood cancer: preliminary observations.4'-去甲基表鬼臼毒素9-(4,6-O-2-亚噻吩基-β-D-吡喃葡萄糖苷)(NSC-122819;VM-26)和4'-去甲基表鬼臼毒素9-(4,6-O-亚乙基-β-D-吡喃葡萄糖苷)(NSC-141540;VP-16-213)用于儿童癌症的初步观察
Cancer Chemother Rep. 1975 Jul-Aug;59(4):743-9.
5
Phase II study of etoposide for carcinoma of the prostate.依托泊苷用于前列腺癌的II期研究。
Cancer Treat Rep. 1986 Jun;70(6):771-2.
6
Phase II evaluation of VP-16-213 (NSC-141540) in patients with advanced ovarian carcinoma resistant to alkylating agents.
Gynecol Oncol. 1978 Feb;6(1):7-9. doi: 10.1016/0090-8258(78)90002-1.
7
Phase II evaluation of etoposide in refractory multiple myeloma: a Southeastern Cancer Study Group Trial.依托泊苷用于难治性多发性骨髓瘤的II期评估:一项东南癌症研究组试验
Cancer Treat Rep. 1986 Jun;70(6):801-2.
8
[Phase II study of etoposide (NK 171) in advanced hematological malignancies].依托泊苷(NK 171)用于晚期血液系统恶性肿瘤的II期研究
Gan To Kagaku Ryoho. 1984 Aug;11(8):1579-84.
9
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
Cancer Treat Rep. 1979 Aug;63(8):1231-9.
10
Podophyllotoxin derivative VP 16-213.鬼臼毒素衍生物VP 16 - 213
Cancer Chemother Pharmacol. 1979;3(2):71-80. doi: 10.1007/BF00254976.

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A new iridoid glycoside and NO production inhibitory activity of compounds isolated from Russelia equisetiformis.从土木香状黄水枝中分离得到的一个新的环烯醚萜苷及具有抑制一氧化氮生成活性的化合物。
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4
Current development of podophyllotoxins.鬼臼毒素的当前发展情况。
Cancer Chemother Pharmacol. 1982;7(2-3):93-8. doi: 10.1007/BF00254528.
5
The clinical pharmacology of VM26 and VP16-213. A brief overview.VM26和VP16 - 213的临床药理学。简要概述。
Cancer Chemother Pharmacol. 1982;7(2-3):133-40. doi: 10.1007/BF00254535.
6
[Etoposide VP 16--213)--a podophyllotoxinderivative with high antitumor activity (author's transl)].依托泊苷(VP 16-213)——一种具有高抗肿瘤活性的鬼臼毒素衍生物(作者译)
Klin Wochenschr. 1981 Nov 2;59(21):1177-88. doi: 10.1007/BF01721212.
7
The clinical pharmacology of etoposide and teniposide.依托泊苷和替尼泊苷的临床药理学
Clin Pharmacokinet. 1987 Apr;12(4):223-52. doi: 10.2165/00003088-198712040-00001.
8
Etoposide and teniposide. Bioanalysis, metabolism and clinical pharmacokinetics.依托泊苷和替尼泊苷。生物分析、代谢及临床药代动力学
Pharm Weekbl Sci. 1988 Jun 17;10(3):101-16. doi: 10.1007/BF01959294.
9
The effect of dose on the bioavailability of oral etoposide.剂量对口服依托泊苷生物利用度的影响。
Cancer Chemother Pharmacol. 1986;16(2):178-81. doi: 10.1007/BF00256172.
10
Podophyllotoxin derivative VP 16-213.鬼臼毒素衍生物VP 16 - 213
Cancer Chemother Pharmacol. 1979;3(2):71-80. doi: 10.1007/BF00254976.