栽培灵芝的成分。
Constituents of cultivated Agaricus blazei.
机构信息
Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
出版信息
J Nat Med. 2011 Apr;65(2):307-12. doi: 10.1007/s11418-010-0495-5. Epub 2011 Jan 18.
PMID:21240679
Abstract
Two phenylhexane derivatives (1, 2), benzoylergostane (3), N-benzoyl-L-leucine methyl ester (4), two known ergostanes, and highly degraded incisterol were isolated from fruit bodies of Agaricus blazei. Compound 3 exhibited strong cytotoxicity toward HepG2 cells (IC(50) = 6.0 ± 0.33 μM).
摘要
从巴西蘑菇的子实体中分离得到了两种苯己烷衍生物（1, 2）、苯甲酰麦角甾烷（3）、N-苯甲酰-L-亮氨酸甲酯（4）、两种已知的麦角甾烷和高度降解的incisterol。化合物 3 对 HepG2 细胞表现出很强的细胞毒性（IC50=6.0±0.33 μM）。
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