Siira Virva, Wahlberg Karl-Erik, Miettunen Jouko, Läksy Kristian, Tienari Pekka
Department of Psychiatry, University of Oulu, Oulu, Finland.
Psychiatry Res. 2008 Apr 15;158(3):278-86. doi: 10.1016/j.psychres.2006.12.005. Epub 2008 Feb 13.
The DSM-III-R diagnoses of a group of adoptees were predicted by the MMPI (Minnesota Multiphasic Personality Inventory) schizophrenia-related scales in the Finnish Adoptive Family Study. The sample consisted of 60 high-risk (HR) adopted-away offspring of biologic mothers with a diagnosis of broad schizophrenia spectrum and 76 low-risk (LR) control adoptees. They were assessed with the MMPI before the onset of any psychiatric disorder at a mean age of 24 years. High scores on the Psychopathic Deviate scale predicted psychiatric disorder at 11-year follow-up. Furthermore, LR adoptees', but not HR adoptees', mental disorders could be predicted with the MMPI scales Psychopathic Deviate and Golden-Meehl Indicators. These scales measure schizophrenia-related personality traits, including a social behavior, anhedonia, ambivalence, interpersonal aversiveness, and formal thought disturbances.
在芬兰收养家庭研究中，通过明尼苏达多相人格调查表（MMPI）中与精神分裂症相关的量表，预测了一组被收养者的《精神疾病诊断与统计手册》第三版修订本（DSM - III - R）诊断结果。样本包括60名高危（HR）被收养者，其生物学母亲被诊断患有广泛精神分裂症谱系疾病，以及76名低危（LR）对照被收养者。他们在平均年龄24岁、尚未出现任何精神疾病之前接受了MMPI评估。在11年的随访中，精神病态偏离量表的高分预示着精神疾病。此外，MMPI量表中的精神病态偏离和戈尔登 - 米尔指标可以预测LR被收养者的精神障碍，但不能预测HR被收养者的精神障碍。这些量表测量与精神分裂症相关的人格特质，包括社交行为、快感缺失、矛盾情绪、人际厌恶和形式思维障碍。
