Zochowski M, Cohen L B, Fuhrmann G, Kleinfeld D
Department of Molecular and Cellular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
J Neurosci. 2000 Nov 15;20(22):8485-92. doi: 10.1523/JNEUROSCI.20-22-08485.2000.
We compared the spike activity of individual neurons in the Aplysia abdominal ganglion with the movement of the gill during the gill-withdrawal reflex. We discriminated four populations that collectively encompass approximately half of the active neurons in the ganglion: (1) second-order sensory neurons that respond to the onset and offset of stimulation of the gill and are active before the movement starts; (2) neurons whose activity is correlated with the position of the gill and typically have a tonic output during gill withdrawal; (3) neurons whose activity is correlated with the velocity of the movement and typically fire in a phasic manner; and (4) neurons whose activity is correlated with both position and velocity. A reliable prediction of the position of the gill is achieved only with the combined output of 15-20 neurons, whereas a reliable prediction of the velocity depends on the combined output of 40 or more cells.
我们将海兔腹神经节中单个神经元的锋电位活动与鳃收缩反射期间鳃的运动进行了比较。我们区分出了四个神经元群体，它们共同涵盖了神经节中约一半的活跃神经元：（1）二阶感觉神经元，对鳃刺激的开始和结束有反应，且在运动开始前就活跃；（2）其活动与鳃的位置相关，且在鳃收缩期间通常有持续性输出的神经元；（3）其活动与运动速度相关，且通常以相位方式放电的神经元；以及（4）其活动与位置和速度都相关的神经元。只有通过15 - 20个神经元的联合输出才能可靠地预测鳃的位置，而对速度的可靠预测则取决于40个或更多细胞的联合输出。
