Matsumoto H, Niimi A, Suzuki K, Kawai M, Matsui Y, Amitani R
Department of Respiratory Medicine, Kyoto University, Kyoto, Japan.
Respiration. 2000;67(5):577-9. doi: 10.1159/000029575.
We describe a case of Churg-Strauss syndrome (CSS) associated with allergic bronchopulmonary candidiasis (ABPC). A 61-year-old man who had been given a diagnosis of ABPC based on serologic and radiographic findings experienced pain and purpuric rash on the left leg accompanied with motor weakness. The diagnosis of CSS was made from skin, nerve and muscle biopsies. Although immunosuppressant and prednisolone were administered and resulted in transient improvement, candidal pneumonia was suspected to have developed 60 days after the administration and the patient finally died of respiratory failure. To our knowledge, this is the first case of CSS associated with ABPC.
我们描述了一例与变应性支气管肺念珠菌病（ABPC）相关的变应性肉芽肿性血管炎（CSS）病例。一名基于血清学和影像学检查结果被诊断为ABPC的61岁男性，左腿出现疼痛和紫癜样皮疹，并伴有运动无力。通过皮肤、神经和肌肉活检确诊为CSS。尽管给予了免疫抑制剂和泼尼松龙治疗并取得了短暂改善，但在用药60天后怀疑发生了念珠菌性肺炎，患者最终死于呼吸衰竭。据我们所知，这是首例与ABPC相关的CSS病例。
