Department of Respiratory Diseases, University Hospital Brno, Jihlavska Str. 20, 62500, Brno, Czech Republic.
Faculty of Medicine, Masaryk University, Brno, Czech Republic.
BMC Pulm Med. 2022 Apr 7;22(1):132. doi: 10.1186/s12890-022-01921-3.
Allergic bronchopulmonary candidiasis (ABPC) is an uncommon clinical syndrome associated with immune hypersensitivity to Candida species.
The case presentation describes a 58-year-old man with acute respiratory failure and bilateral lung infiltrates. Due to high inflammatory markers and a chest X-ray indicating lung infiltration, he was initially treated for pneumonia with combined antibiotics. Despite comprehensive treatment at the ICU, the patient's clinical status deteriorated rapidly, and further investigations provided a rare diagnosis of ABPC. After several days of combined corticosteroid and antifungal therapy, we observed rapid clinical improvement and subsequent resolution of the pulmonary infiltrates.
This case report presented a rare case of ABPC mimicking bilateral pneumonia and acute respiratory failure. Our case highlighted the importance of prompt corticosteroid and antifungal treatment initiation as it resulted in rapid clinical improvement and a near complete reversal of the bilateral lung infiltrates.
过敏性支气管肺念珠菌病（ABPC）是一种与对念珠菌属的免疫过敏相关的罕见临床综合征。
该病例描述了一位 58 岁男性，因急性呼吸衰竭和双肺浸润就诊。由于炎症标志物升高和 X 光胸片提示肺部浸润，他最初接受了联合抗生素治疗肺炎。尽管在重症监护病房进行了全面治疗，但患者的临床状况迅速恶化，进一步的检查提供了一个罕见的 ABPC 诊断。在接受数天的皮质类固醇和抗真菌联合治疗后，我们观察到快速的临床改善和随后肺部浸润的消退。
本病例报告呈现了一个罕见的 ABPC 病例，表现为双侧肺炎和急性呼吸衰竭。我们的病例强调了及时启动皮质类固醇和抗真菌治疗的重要性，因为它导致了快速的临床改善和双侧肺部浸润的几乎完全逆转。
