腹腔镜与开腹胆囊切除术后患者急性期反应物的比较：一项随机研究
Comparison of postoperative acute-phase reactants in patients who underwent laparoscopic v open cholecystectomy: a randomized study.
作者信息
Demirer S, Karadayi K, Simşek S, Erverdi N, Bumin C
机构信息
Department of Surgery, Ankara University Medical School, Ibn-i Sina Hospital, Turkey.
出版信息
J Laparoendosc Adv Surg Tech A. 2000 Oct;10(5):249-52. doi: 10.1089/lap.2000.10.249.
PURPOSE
We investigated the effect of laparoscopic v open cholecystectomy on acute-phase reactants.
PATIENTS AND METHODS
Fifty patients were randomized to laparoscopic (Group 1) and 50 to open (Group 2) cholecystectomy. Preoperative and postoperative values for acute-phase reactants (ceruloplasmin, fibrinogen, Westergren sedimentation rate, alpha-1-antitrypsin, haptoglobin, and C-reactive protein) in blood samples were compared.
RESULTS
Acute-phase reactants and length of hospitalization were significantly lower in patients who underwent a laparoscopic cholecystectomy than in those who underwent an open cholecystectomy.
CONCLUSION
Laparoscopic cholecystectomy appears associated with a less intense stress response and less tissue damage than open cholecystectomy.
目的
我们研究了腹腔镜胆囊切除术与开腹胆囊切除术对急性期反应物的影响。
患者与方法
50例患者被随机分为接受腹腔镜胆囊切除术组（第1组）和50例接受开腹胆囊切除术组（第2组）。比较两组患者血液样本中急性期反应物（铜蓝蛋白、纤维蛋白原、魏氏血沉率、α-1抗胰蛋白酶、触珠蛋白和C反应蛋白）的术前和术后值。
结果
接受腹腔镜胆囊切除术的患者急性期反应物水平和住院时间显著低于接受开腹胆囊切除术的患者。
结论
与开腹胆囊切除术相比，腹腔镜胆囊切除术似乎与较轻的应激反应和较少的组织损伤有关。
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