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作为一种表面现象的吞噬作用。五、鼠伤寒沙门氏菌粗糙型和平滑型菌株的接触角与吞噬作用,以及特异性抗血清的影响。

Phagocytosis as a surface phenomenon. V. Contact angles and phagocytosis of rough and smooth strains of Salmonella typhimurium, and the influence of specific antiserum.

作者信息

Cunningham R K, Söderström T O, Gillman C F, van Oss C J

出版信息

Immunol Commun. 1975;4(5):429-42. doi: 10.3109/08820137509057331.

DOI:10.3109/08820137509057331
PMID:1107214
Abstract

The angle made by a drop of saline in contact with a monolayer of Salmonella typhimurium or phagocytic cells, the contact angle, is a measure of their relative interfacial tension, and is predictive of a successful phagocytosis. Smooth strains of S. typhimurium possess a contact angle lower than the phagocytic cells and resist phagocytosis. Rough strains have an angle higher than the phagocytes and are readily engulfed. The lower contact angle of smooth strains can be increased by treatment with specific antibody resulting in more efficient phagocytosis.

摘要

一滴生理盐水与鼠伤寒沙门氏菌单层或吞噬细胞接触形成的角度,即接触角,是它们相对界面张力的一种度量,并且可预测吞噬作用是否成功。鼠伤寒沙门氏菌的光滑菌株的接触角低于吞噬细胞,因而能抵抗吞噬作用。粗糙菌株的接触角高于吞噬细胞,容易被吞噬。光滑菌株较低的接触角可通过用特异性抗体处理而增大,从而导致更有效的吞噬作用。

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