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接触粉尘对水泥厂工人肺功能的影响。

Effect of exposure to dust on lung function of cement factory workers.

作者信息

Noor H, Yap C L, Zolkepli O, Faridah M

机构信息

Jabatan Biologi, Fakulti Sains dan Pengajian Alam Sekitar, Universiti Putra Malaysia, Selangor.

出版信息

Med J Malaysia. 2000 Mar;55(1):51-7.

PMID:11072491
Abstract

Exposure to Portland cement dust has long been associated with the prevalence of respiratory symptoms and varying degrees of airway obstruction in man. Apart from respiratory diseases, it was also found to be the cause of lung and laryngeal cancer, gastrointestinal tumours and also dermatitis. This study was done to investigate the effect of dust exposure on ventilatory lung function of Portland cement factory workers in Rawang, Selangor. Spirometry tests of 62 male workers (exposed to total dust concentration of 10,180 micrograms/m3 and PM10 of 8049 micrograms/m3) and 70 subjects from UPM (exposed to mean total dust of 192 micrograms/m3 and PM10 of 177 micrograms/m3--controls) revealed significant differences in spirometry values between the groups. The workers showed i) significantly lower FEV1% and FEF25-75%, and higher FMFT, ii) reduced FEV1% with increasing level of dust exposure and iii) higher prevalence of respiratory symptoms. Therefore, we suggest that exposure to dust in the cement factory leads to higher incidence of respiratory symptoms and impaired lung function.

摘要

长期以来,接触波特兰水泥粉尘一直与人类呼吸道症状的普遍存在以及不同程度的气道阻塞有关。除了呼吸系统疾病外,还发现它是肺癌、喉癌、胃肠道肿瘤以及皮炎的病因。本研究旨在调查雪兰莪瓜拉冷岳波特兰水泥厂工人接触粉尘对肺通气功能的影响。对62名男性工人(接触总粉尘浓度为10180微克/立方米,PM10为8049微克/立方米)和70名来自马来西亚博特拉大学的受试者(接触平均总粉尘192微克/立方米,PM10为177微克/立方米——对照组)进行的肺活量测定测试显示,两组之间的肺活量测定值存在显著差异。工人们表现出:i)FEV1%和FEF25-75%显著降低,FMFT升高;ii)随着粉尘接触水平的增加,FEV1%降低;iii)呼吸道症状的患病率更高。因此,我们认为水泥厂的粉尘接触会导致呼吸道症状的发病率更高和肺功能受损。

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