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刚果中央省接触水泥粉尘的水泥工人中慢性阻塞性肺疾病(COPD)的患病率。

Prevalence of chronic obstructive pulmonary disease (COPD) among Congolese cement workers exposed to cement dust, in Kongo Central Province.

机构信息

Department of Environmental Medicine, Kochi University Medical School, Oko-cho Kohasu, Nankoku, Kochi, 783-8505, Japan.

Department of Gynecology and Obstetrics, University of Kinshasa, Kinshasa, Democratic Republic of Congo.

出版信息

Environ Sci Pollut Res Int. 2018 Dec;25(35):35074-35083. doi: 10.1007/s11356-018-3401-4. Epub 2018 Oct 16.

Abstract

Chronic exposure to cement dust may induce adverse health effects, including a significant decrease in lung function. The study investigated whether the prevalence of COPD and respiratory symptoms was associated with working at different tasks exposed to varying levels of cement dust. The cross-sectional study was carried out among 223 exposed and 156 less exposed workers from two cement factories from November 20 to December 15, 2016 in DRC. Workers completed a questionnaire and spirometry was performed. Multivariate analysis was performed to evaluate the association between occupation exposed to cement dust, COPD, and respiratory symptoms, after adjustment for confounders. Morning cough and cough on most days for as much as 3 months each year were significantly higher in the exposed group (p < 0.05) (p = 0.001) than in the less exposed group. As compared to the less exposed group, the prevalence of COPD was higher among the exposed group, 28.2 and 9.6% respectively (p < 0.001). A significant association with COPD, aOR 14.49 (5.33; 39.40), aOR 3.37 (1.44; 7.89), and aOR 3.09 (1.58; 6.05) was found among cleaning, transportation, and production workers, respectively. Working at certain tasks exposed to cement dust is associated with the higher prevalence of COPD and respiratory symptoms. A greater risk is being among cleaning, transportation, and production workers. This suggests the necessity to prioritize the quality of preventive measures in each work area.

摘要

慢性暴露于水泥粉尘可能会引起不良健康影响,包括肺功能显著下降。本研究调查了 COPD 和呼吸道症状的患病率是否与暴露于不同水平水泥粉尘的不同工作任务有关。这项横断面研究于 2016 年 11 月 20 日至 12 月 15 日在刚果民主共和国的两家水泥厂进行,共纳入了 223 名暴露工人和 156 名低暴露工人。工人们完成了一份问卷,并进行了肺量测定。进行了多变量分析,以评估在调整混杂因素后,暴露于水泥粉尘的职业、COPD 和呼吸道症状之间的关联。暴露组工人中,早晨咳嗽和每年最多咳嗽 3 个月、每天咳嗽的比例明显高于低暴露组(p<0.05)(p=0.001)。与低暴露组相比,暴露组的 COPD 患病率更高,分别为 28.2%和 9.6%(p<0.001)。与 COPD 显著相关的是,清洁工、运输工和生产工的优势比(OR)分别为 14.49(5.33;39.40)、3.37(1.44;7.89)和 3.09(1.58;6.05)。在清洁、运输和生产工人中分别发现了与 COPD 和呼吸道症状的更高患病率之间存在显著关联。在清洁工、运输工和生产工中,风险更高。这表明有必要在每个工作区域优先考虑预防措施的质量。

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