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希腊水泥生产工人肺功能损害的患病率:一项横断面研究。

Prevalence of lung function impairment among Greek cement production workers: a cross-sectional study.

作者信息

Rachiotis George, Kostikas Konstantinos, Pinotsi Dimitra, Hadjichristodoulou Christos, Drivas Spyros

机构信息

Department of Hygiene and Epidemiology, Medical Faculty, University of Thessaly, Greece.

Greek Institute for Occupational Safety and Health, Greece.

出版信息

Ind Health. 2018 Feb 7;56(1):49-52. doi: 10.2486/indhealth.2017-0005. Epub 2017 Aug 22.

DOI:10.2486/indhealth.2017-0005
PMID:28835577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5800865/
Abstract

Greece is a significant cement producing country. The aim of this study was to investigate the prevalence and risk factors of lung function impairment among Greek cement workers. One hundred thirty- seven cement production workers participated in this study. In addition, 110 employees not exposed to cement dust comprised the control group. The concentration of cement total dust at workplace varied from 1.1 to 11.6 mg/m. In only one of the measurements, the Threshold Limit Level of 10 mg/m has been exceeded. Cement production workers presented a higher prevalence of FEV1<80% in comparison to controls (13.9% vs. 2.7%; Chi-Square Test; p=0.002). Multivariate analysis has shown that cement production workers have recorded an almost 5 fold risk of low lung function, as expressed by FEV1<80%, in comparison to the reference population OR=4.92; 95% C.I.=1.22-12.62). Current smoking was associated with an almost 4- fold increased risk of FEV1<80% (OR=3.91;95% C.I.=1.32-11.56). In conclusion, we found a high prevalence of impaired lung function among Greek cement production workers, despite the fact that total and inhalable dust levels were below the occupational exposure limits.

摘要

希腊是一个重要的水泥生产国。本研究的目的是调查希腊水泥工人肺功能损害的患病率及危险因素。137名水泥生产工人参与了本研究。此外,110名未接触水泥粉尘的员工组成了对照组。工作场所水泥总粉尘浓度在1.1至11.6毫克/立方米之间。仅在一次测量中超过了10毫克/立方米的阈限值。与对照组相比,水泥生产工人中FEV1<80%的患病率更高(13.9%对2.7%;卡方检验;p=0.002)。多变量分析表明,与参考人群相比,水泥生产工人出现肺功能低下(以FEV1<80%表示)的风险几乎高出5倍(OR=4.92;95%置信区间=1.22 - 12.62)。当前吸烟与FEV1<80%的风险增加近4倍相关(OR=3.91;95%置信区间=1.32 - 11.56)。总之,我们发现希腊水泥生产工人中肺功能受损的患病率很高,尽管总粉尘和可吸入粉尘水平低于职业接触限值。