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马来西亚1型人类免疫缺陷病毒感染受试者戊型肝炎病毒感染的血清流行率研究。

A seroprevalence study of viral hepatitis E infection in human immunodeficiency virus type 1 infected subjects in Malaysia.

作者信息

Ng K P, He J, Saw T L, Lyles C M

机构信息

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Med J Malaysia. 2000 Mar;55(1):58-64.

PMID:11072492
Abstract

Hepatitis E virus (HEV) is a RNA virus transmitted enterically. A study of anti-HEV antibodies in 145 human immunodeficiency virus type 1 (HIV-1) infected subjects found that 14.4% of them were reactive to anti-HEV antibodies. Anti-HEV IgG and anti-HEV IgM was detected in 10.3% and 4.1% of the subjects respectively. Prevalence of anti-HEV (either IgG or IgM) was similar across all adult ages (p = 0.154), between the three ethnic groups (p = 0.378), and across risk groups (p = 0.120). The results showed that HEV infection in subjects recruited in this study was most likely transmitted via faecal-route.

摘要

戊型肝炎病毒(HEV)是一种经肠道传播的RNA病毒。一项针对145名1型人类免疫缺陷病毒(HIV-1)感染者的抗HEV抗体研究发现,其中14.4%的人抗HEV抗体呈阳性反应。分别在10.3%和4.1%的受试者中检测到抗HEV IgG和抗HEV IgM。在所有成年人年龄组中(p = 0.154)、三个种族群体之间(p = 0.378)以及不同风险组中(p = 0.120),抗HEV(IgG或IgM)的流行率相似。结果表明,本研究招募的受试者中的HEV感染很可能是通过粪口途径传播的。

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