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埃及上埃及农村地区五岁以下儿童腹泻病的发病率及危险因素

Morbidity and risk factors of diarrheal diseases among under-five children in rural Upper Egypt.

作者信息

Yassin K

机构信息

Department 2: Public Health Medicine, School of Public Health, University of Bielefeld, Germany.

出版信息

J Trop Pediatr. 2000 Oct;46(5):282-7. doi: 10.1093/tropej/46.5.282.

DOI:10.1093/tropej/46.5.282
PMID:11077937
Abstract

Diarrhea is a leading cause of mortality and morbidity in developing countries. In Egypt, researchers have traditionally been targeting diarrhea-related mortality. This study is an attempt to portray the morbidity and risk factors of diarrhea among children under 5 years old (under-fives) in rural Upper Egypt. The incidence of diarrhea in the 6 months before the study was determined among 1025 under-fives in six sentinel sites by interviewing mothers or caretakers. The association between diarrhea and a set of risk variables was examined using a multivariate logistic regression model. Variables that appeared to have a significant predictive power were then included in a forward wald stepwise logit analysis model to estimate statistical functions which best predict the diarrheal morbidity. The incidence rate of diarrhea was found to be 3.6 episodes per child semiannually and the point prevalence was 19.5 per cent. The average duration of current episodes was 4.8 +/- 3.7 days; 33.6 per cent of children had had diarrhea more than three times (recurrent diarrhea). Four variables were found to have a significant association with recurrent diarrhea. The logit coefficients and their significance levels indicated that, in order of contribution to risk prediction, the variables ranked as follows: household meat consumption, mother's age at the time of birth of the child, child's age, and father's illiteracy. A total of 74.8 per cent of overall children were correctly predicted by these risk factors, a figure which indicates the goodness of fit of the model. It is concluded that the diarrheal morbidity is still unacceptably high in rural Upper Egypt. More interventions are needed to control for specific risk factors.

摘要

腹泻是发展中国家死亡和发病的主要原因。在埃及,研究人员传统上一直关注与腹泻相关的死亡率。本研究旨在描述埃及上埃及农村地区5岁以下儿童(五岁以下儿童)腹泻的发病率及风险因素。通过访谈母亲或照料者,在六个哨点的1025名五岁以下儿童中确定了研究前6个月的腹泻发病率。使用多变量逻辑回归模型检验腹泻与一组风险变量之间的关联。然后将似乎具有显著预测能力的变量纳入向前wald逐步逻辑分析模型,以估计最能预测腹泻发病率的统计函数。腹泻发病率为每名儿童每半年3.6次,点患病率为19.5%。当前发作的平均持续时间为4.8 +/- 3.7天;33.6%的儿童腹泻超过三次(复发性腹泻)。发现有四个变量与复发性腹泻有显著关联。逻辑系数及其显著性水平表明,按对风险预测的贡献顺序,变量排名如下:家庭肉类消费、孩子出生时母亲的年龄、孩子的年龄和父亲的文盲程度。这些风险因素正确预测了74.8%的总体儿童,这一数字表明了模型的拟合优度。得出的结论是,埃及上埃及农村地区的腹泻发病率仍然高得令人无法接受。需要采取更多干预措施来控制特定的风险因素。

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