Blanco A, Artacho-Pérula E, Roldán-Villalobos R, Monterde J G
Department of Comparative and Pathological Anatomy, Veterinary Faculty, University of Córdoba, Spain.
Vet Rec. 2000 Oct 14;147(16):447-51. doi: 10.1136/vr.147.16.447.
Stereological methods were used to investigate the morphometric variations in the adrenal cell population of calves dosed orally with clenbuterol at an anabolic dose of 20 microg/kg bodyweight per day for 12 weeks. In the treated group the size of the nuclei increased with respect to the control group, and the increases were significant for the maximum linear parameters in all the regions except the zona fasciculata. The largest increases were observed in the epinephrine-producing cells. The quantitative stereological data showed highly significant increases in the nuclear volume fraction, the nuclear surface density and the numerical density in the zona fasciculata of the treated group.
采用体视学方法研究了犊牛口服克伦特罗(剂量为每天20微克/千克体重,为合成代谢剂量,持续12周)后肾上腺细胞群体的形态计量学变化。在治疗组中,细胞核大小相对于对照组有所增加,除束状带外,所有区域的最大线性参数增加均具有显著性。肾上腺素产生细胞的增加最为明显。定量体视学数据显示,治疗组束状带的核体积分数、核表面密度和数值密度均有极显著增加。