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94例脓胸行胸膜外全肺切除术后的发病率和死亡率。

Morbidity and mortality after 94 extrapleural pneumonectomies for empyema.

作者信息

Shiraishi Y, Nakajima Y, Koyama A, Takasuna K, Katsuragi N, Yoshida S

机构信息

Section of Chest Surgery, Fukujuji Hospital, Kiyose, Tokyo, Japan.

出版信息

Ann Thorac Surg. 2000 Oct;70(4):1202-6; discussion 1206-7. doi: 10.1016/s0003-4975(00)01612-x.

Abstract

BACKGROUND

Extrapleural pneumonectomy is still indicated in some patients with empyema. We examined morbidity and mortality after this high-risk operation.

METHODS

Between 1979 and 1998, 94 (92 chronic, 2 postsurgical) patients with empyema underwent extrapleural pneumonectomy. There were 79 men and 15 women (mean age, 59 years). Eighty-eight patients had a history of tuberculosis, and 53 had undergone a therapeutic pneumothorax. The right side was operated on in 50 patients and left in 44.

RESULTS

Operative mortality was 8.5%. Fifteen major complications (1 esophageal perforation, 9 empyemas, and 5 bronchopleural fistulas) occurred in 13 patients. Eight patients required reexploration for hemorrhage. Reexploration was a risk factor for empyema. Bronchopleural fistulas occurred only on the right side. Eighty-nine percent of the 86 operative survivors were free of empyemas at 5 years. Overall 5-year survival was 83%, and survival was better in patients without than in those with empyema.

CONCLUSIONS

Extrapleural pneumonectomy for empyema has acceptable morbidity and mortality. Postoperative empyema affects prognosis. Covering a bronchial stump with muscle is recommended, especially when the operation is performed on the right side.

摘要

背景

对于某些脓胸患者,仍需行胸膜外全肺切除术。我们研究了这一高风险手术后的发病率和死亡率。

方法

1979年至1998年间,94例(92例慢性脓胸,2例术后脓胸)脓胸患者接受了胸膜外全肺切除术。其中男性79例,女性15例(平均年龄59岁)。88例患者有结核病史,53例曾接受过治疗性气胸治疗。50例患者接受右侧手术,44例接受左侧手术。

结果

手术死亡率为8.5%。13例患者出现15种主要并发症(1例食管穿孔、9例脓胸和5例支气管胸膜瘘)。8例患者因出血需要再次手术探查。再次手术探查是发生脓胸的危险因素。支气管胸膜瘘仅发生在右侧。86例手术存活者中,89%在5年时无脓胸。总体5年生存率为83%,无脓胸患者的生存率高于有脓胸患者。

结论

胸膜外全肺切除术治疗脓胸的发病率和死亡率可接受。术后脓胸影响预后。建议用肌肉覆盖支气管残端,尤其是在右侧手术时。

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