Hanke W, Sobala W, Kalinka J
Zakładu Epidemiologii Srodowiskowej, Instytutu Medycyny Pracy w Lodzi.
Ginekol Pol. 2000 Aug;71(8):833-6.
The main goal of the project was to estimate the effect of environmental tobacco smoke (ETS) exposure on the birthweight. In a cohort of 196 pregnant women in 20-24 week of pregnancy the serum and urine cotinine levels were determined. The cohort included randomly selected pregnant patients of a maternity units in Lodz, Poland. To assess a 24 h exposure to ETS preceding the day of examination, both serum and urine cotinine measurements were applied. A statistically significant relationship was found between serum cotinine concentration and brithweight. The newborns of nonsmoking mothers whose serum cotinine levels were characteristic for passive smoking (2-25 ng/ml) had their birthweight lower by an average of 30 g, compared to those of women who were not exposed to ETS (serum cotinine below 2 ng/ml). It was concluded that more effective public health measures should be undertaken to ensure a tobacco smoke-free environment for pregnant women. Until this goal is achieved, pregnant women should be informed about health risks from ETS exposure so that they would avoid it both at home and workplace.
该项目的主要目标是评估环境烟草烟雾（ETS）暴露对出生体重的影响。在一组196名处于妊娠20 - 24周的孕妇中，测定了血清和尿液中的可替宁水平。该队列包括波兰罗兹一家产科病房随机选取的孕妇患者。为了评估检查前一天24小时的ETS暴露情况，同时采用了血清和尿液可替宁测量方法。发现血清可替宁浓度与出生体重之间存在统计学上的显著关系。与未暴露于ETS（血清可替宁低于2 ng/ml）的女性相比，血清可替宁水平具有被动吸烟特征（2 - 25 ng/ml）的非吸烟母亲所生新生儿的出生体重平均低30克。得出的结论是，应采取更有效的公共卫生措施，为孕妇确保无烟环境。在实现这一目标之前，应告知孕妇ETS暴露的健康风险，以便她们在家中和工作场所都能避免接触。
