Lenkiewicz B
Zakładu Immunologii Hematologicznej i Transfuzjologicznej Instytutu Hematologii i Transfuzjologii w Warszawie.
Ginekol Pol. 2000 Aug;71(8):863-8.
Results of antibody investigations during pregnancy in 348,040 women were summared. Immune alloantibody were stated in 3053 women (0.9%): in 2437 anti-D (1.6% of Rh negative) and in 606 other immune antibodies. The reasons of the D antigen immunization were analysed. Anti-D activity by chemiluminescence test (CLT) in 45 women, qualified to cordocentesis, were presented. The results compared to the fetal anaemia indicated that in women with high titer (32 or higher), CLT could diminish invasive diagnostics.
总结了348,040名女性孕期抗体检测结果。3053名女性(0.9%)检测出免疫同种抗体:其中2437名女性检测出抗-D抗体(占Rh阴性女性的1.6%),606名女性检测出其他免疫抗体。分析了D抗原免疫的原因。列出了45名符合脐血穿刺条件女性的化学发光试验(CLT)抗-D活性结果。将结果与胎儿贫血情况进行比较,结果表明,对于高滴度(32及以上)女性,CLT可减少侵入性诊断。