Wade W E, Chisholm M A
Department of Clinical and Administrative Sciences, College of Pharmacy, University of Georgia, Athens 30602, USA.
Am J Phys Med Rehabil. 2000 Nov-Dec;79(6):504-8. doi: 10.1097/00002060-200011000-00003.
Venous thrombosis and pulmonary embolisms are major complications associated with acute spinal cord injury. The purpose of this study was to perform a cost analysis on the two pharmacoprophylaxis regimens suggested for deep vein thrombosis prophylaxis in this population.
Efficacy and safety data were obtained from the literature.
Results of the cost analysis demonstrates that adjusted dose unfractionated heparin produces a cost savings over enoxaparin at 30 mg every 12 hr.
Further studies are needed to determine the most cost-effective therapy for preventing deep vein thrombi in this population.
静脉血栓形成和肺栓塞是急性脊髓损伤的主要并发症。本研究的目的是对针对该人群预防深静脉血栓形成建议的两种药物预防方案进行成本分析。
从文献中获取疗效和安全性数据。
成本分析结果表明，调整剂量的普通肝素比每12小时30毫克的依诺肝素节省成本。
需要进一步研究以确定该人群预防深静脉血栓形成的最具成本效益的治疗方法。
