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[在内窥镜化学消毒过程中戊二醛的职业暴露]

[Occupational exposure to glutaraldehyde during its use in chemical disinfection of endoscopes].

作者信息

Apostoli P

出版信息

Minerva Med. 2000 May-Jun;91(5-6):127-32.

PMID:11084848
Abstract

BACKGROUND

To evaluate the air pollution experimentally produced by different solutions of glutaraldehyde due to the activity of chemical disinfection in a flexible endoscopy unit.

METHODS

The glutaraldehyde environment concentrations due to the use of 3 solutions (2% solution and its 1:5 and 1:20 dilutions) were measured by liquid chromatography after sampling on specific cartridges and by fotoacoustic method.

RESULTS

Only after the use of the most concentrated solution it was possible to detect glutaraldehyde in the environment air, with values between 0.2 and 0.3 mg/m3 and during specific activities such as after shaking the disinfecting solutions.

CONCLUSIONS

When the usual preventive recommendations are respected, the use of 1:5 and 1:20 solution of 2% glutaraldehyde products does not produce air concentrations of the aldehyde exceeding the current, even restrictive, limits proposed by industrial hygienists.

摘要

背景

评估在一个软式内镜检查单元中,不同浓度戊二醛溶液进行化学消毒时所产生的空气污染情况。

方法

通过在特定滤筒上采样后用液相色谱法以及光声法,测量使用3种溶液(2%溶液及其1:5和1:20稀释液)时环境中戊二醛的浓度。

结果

仅在使用最浓溶液后,才有可能在环境空气中检测到戊二醛,其值在0.2至0.3毫克/立方米之间,且在特定活动期间,如摇晃消毒溶液后会出现。

结论

当遵循常规的预防建议时,使用2%戊二醛产品的1:5和1:20稀释液不会使环境空气中醛的浓度超过工业卫生学家目前提出的、甚至是严格的限值。

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