Caradona S A, Skidmore R, Gupta A, Bush C H, Ford M J
Department of Dermatology, University of Florida College of Medicine, Gainesville, USA.
Pediatr Dermatol. 2000 Sep-Oct;17(5):387-90. doi: 10.1046/j.1525-1470.2000.017005387.x.
A 17-week-old boy with a giant congenital melanocytic nevus (GCMN) of the left lower extremity was noted to have a reduction in circumference of the left lower extremity relative to the contralateral side. The skin overlying the GCMN was persistently warm when compared with the surrounding and contralateral skin. Comparative plain radiography, ultrasonography, and magnetic resonance imaging showed fat hypoplasia of the left lower extremity, with bone and muscle appearing unaffected. The possible role of cytokines produced by the nevus in fat hypoplasia in GCMN is discussed.
一名17周大的男孩，左下肢患有巨大先天性黑素细胞痣（GCMN），其左下肢周长相对于对侧有所减小。与周围及对侧皮肤相比，覆盖GCMN的皮肤持续发热。对比X线平片、超声和磁共振成像显示左下肢脂肪发育不全，骨骼和肌肉未受影响。文中讨论了痣产生的细胞因子在GCMN脂肪发育不全中的可能作用。
