Itin P H, Lautenschlager S
Department of Dermatology, University of Basel, Switzerland.
Pediatr Dermatol. 1998 Jul-Aug;15(4):287-9. doi: 10.1046/j.1525-1470.1998.1998015287.x.
Giant congenital melanocytic nevi (GCMN) may be associated with a variety of malformations. Recently, atrophy of the underlying extremity was reported for the first time. We observed two patients with GCMN on the extremities with marked atrophy of the underlying tissue without functional impairment. According to the definition of hamartoma, it seems possible that one component of tissue has decreased. Dermatologists treating patients with such nevi in the first weeks of life with dermabrasion, laser, or curettage need to know that the natural course of GCMN may lead to atrophy and that this does not necessarily result from the treatment regimen.
巨大先天性黑素细胞痣（GCMN）可能与多种畸形相关。最近，首次报道了其下方肢体的萎缩情况。我们观察到两名患有肢体GCMN的患者，其下方组织明显萎缩但无功能障碍。根据错构瘤的定义，似乎有可能一种组织成分减少了。在出生后第一周就用磨皮术、激光或刮除术治疗此类痣患者的皮肤科医生需要知道，GCMN的自然病程可能会导致萎缩，而这不一定是由治疗方案引起的。
