Mukku V J, Speitling M, Laatsch H, Helmke E
Department of Organic Chemistry, University of Goettingen, Tammannstrasse 2, D-37077 Goettingen, Germany.
J Nat Prod. 2000 Nov;63(11):1570-2. doi: 10.1021/np0001676.
Chemical examination of two marine Streptomycetes has resulted in the isolation of four new butenolides, namely 4, 10-dihydroxy-10-methyl-dodec-2-en-1,4-olide (1), two diastereomeric 4,11-dihydroxy-10-methyl-dodec-2-en-1,4-olides (2/3), and 4-hydroxy-10-methyl-11-oxo-dodec-2-en-1,4-olide (4). The structures were identified by interpretation of the 2D NMR and mass spectral data.
对两种海洋链霉菌进行化学分析后，分离出了四种新的丁烯内酯，即4,10 - 二羟基 - 10 - 甲基 - 十二碳 - 2 - 烯 - 1,4 - 内酯（1）、两种非对映体的4,11 - 二羟基 - 10 - 甲基 - 十二碳 - 2 - 烯 - 1,4 - 内酯（2/3）以及4 - 羟基 - 10 - 甲基 - 11 - 氧代 - 十二碳 - 2 - 烯 - 1,4 - 内酯（4）。通过对二维核磁共振和质谱数据的解析确定了其结构。
