Aiello A, Carbonelli S, Esposito G, Fattorusso E, Iuvone T, Menna M
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, via D. Montesano 49, I-80131, Napoli, Italy.
J Nat Prod. 2000 Nov;63(11):1590-2. doi: 10.1021/np000281o.
Three sulfated alkene and alkanes-(R)-2,6-dimethylheptyl sulfate (1), 6-methylheptyl sulfate (2a), and (E)-5-octenyl sulfate (3a)-with cytotoxic activity in vitro, have been isolated from the Mediterranean ascidian Halocynthia papillosa. The structures of the new compounds 2a and 3a have been elucidated by spectroscopic analysis.
从地中海海鞘Halocynthia papillosa中分离出了三种具有体外细胞毒性活性的硫酸化烯烃和烷烃——(R)-2,6-二甲基庚基硫酸酯(1)、6-甲基庚基硫酸酯(2a)和(E)-5-辛烯基硫酸酯(3a)。新化合物2a和3a的结构已通过光谱分析得以阐明。