荷兰包涵体肌炎的流行病学：一项全国性研究。

Epidemiology of inclusion body myositis in the Netherlands: a nationwide study.

作者信息

Badrising U A, Maat-Schieman M, van Duinen S G, Breedveld F, van Doorn P, van Engelen B, van den Hoogen F, Hoogendijk J, Höweler C, de Jager A, Jennekens F, Koehler P, van der Leeuw H, de Visser M, Verschuuren J J, Wintzen A R

机构信息

Department of Neurology, Leiden University Medical Center, The Netherlands.

出版信息

Neurology. 2000 Nov 14;55(9):1385-7. doi: 10.1212/wnl.55.9.1385.

DOI:10.1212/wnl.55.9.1385

PMID:11087787

Abstract

Epidemiologic data on inclusion body myositis (IBM) are scarce, and possibly biased, because they are derived from larger neuromuscular centers. The present nationwide collaborative cross-sectional study, which culminated on July 1, 1999, resulted in identification of 76 patients with IBM and the establishment of a prevalence of 4.9 patients with IBM per million inhabitants in the Netherlands. Several discrepancies suggest that this may be an underestimation. The most frequently identified pitfall in diagnosing IBM was an erroneous diagnosis of polymyositis or motor neuron disease.

摘要

关于包涵体肌炎（IBM）的流行病学数据稀缺，且可能存在偏差，因为这些数据来自较大的神经肌肉中心。这项于1999年7月1日结束的全国性合作横断面研究，最终确定了76例IBM患者，并得出荷兰每百万居民中IBM患者的患病率为4.9例。一些差异表明这可能是低估。诊断IBM时最常出现的失误是将其误诊为多发性肌炎或运动神经元病。