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内源性逆转录病毒与人类种系

Endogenous retroviruses and the human germline.

作者信息

Bock M, Stoye J P

机构信息

Division of Virology, National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.

出版信息

Curr Opin Genet Dev. 2000 Dec;10(6):651-5. doi: 10.1016/s0959-437x(00)00138-6.

DOI:10.1016/s0959-437x(00)00138-6
PMID:11088016
Abstract

The human genome is rife with the proviral remains of many ancient retroviruses. The past year has seen significant progress in understanding the structure, distribution and potential function of many of these elements. Although hypotheses concerning the potential effects of these elements are common, however, incisive experiments to test any functions remain much less so.

摘要

人类基因组中充斥着许多古代逆转录病毒的前病毒遗迹。在过去一年里,人们对其中许多元件的结构、分布和潜在功能的理解取得了重大进展。然而,尽管关于这些元件潜在影响的假说是常见的,但用以检验其任何功能的精确实验却少得多。

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