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患有全身炎症反应综合征或脓毒症的重症监护病房患者发生危重病性多神经病的早期迹象。

Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsis.

作者信息

Tennilä A, Salmi T, Pettilä V, Roine R O, Varpula T, Takkunen O

机构信息

Department of Anaesthesia and Intensive Care, Helsinki University Hospital, Finland.

出版信息

Intensive Care Med. 2000 Sep;26(9):1360-3. doi: 10.1007/s001340000586.

DOI:10.1007/s001340000586
PMID:11089765
Abstract

OBJECTIVE

To evaluate with electromyography the incidence and the time of appearance of neuromuscular abnormality in patients with systemic inflammatory response syndrome (SIRS) and/or sepsis.

DESIGN

Follow-up study.

SETTING

Intensive care unit of Helsinki University Hospital, Finland.

PATIENTS

Nine mechanically ventilated patients with SIRS and/or sepsis.

INTERVENTIONS

Electromyography and conduction velocity measurements on the 2nd-5th day after admission to the intensive care unit.

MEASUREMENTS AND RESULTS

In all nine patients electromyography revealed signs of neuromuscular abnormality. The means of compound muscle action potential amplitudes of the median and ulnar nerves were decreased. Fibrillation was observed in four patients out of nine.

CONCLUSION

Because neuromuscular abnormalities seem to develop earlier than previously reported, electroneuromyography should be used more frequently as a diagnostic test.

摘要

目的

通过肌电图评估全身炎症反应综合征(SIRS)和/或脓毒症患者神经肌肉异常的发生率及出现时间。

设计

随访研究。

地点

芬兰赫尔辛基大学医院重症监护病房。

患者

9例机械通气的SIRS和/或脓毒症患者。

干预措施

在入住重症监护病房后的第2至5天进行肌电图和传导速度测量。

测量与结果

所有9例患者的肌电图均显示神经肌肉异常迹象。正中神经和尺神经的复合肌肉动作电位振幅均值降低。9例患者中有4例观察到纤颤。

结论

由于神经肌肉异常似乎比先前报道的出现更早,因此应更频繁地使用神经肌电图作为诊断测试。

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Intensive Care Med. 2000 Sep;26(9):1360-3. doi: 10.1007/s001340000586.
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