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Association between acute hypobaric hypoxia and activation of coagulation in human beings.

作者信息

Bendz B, Rostrup M, Sevre K, Andersen T O, Sandset P M

出版信息

Lancet. 2000 Nov 11;356(9242):1657-8. doi: 10.1016/S0140-6736(00)03165-2.

DOI:10.1016/S0140-6736(00)03165-2
PMID:11089830
Abstract

The risk of venous thrombosis is thought to be increased by flying. In a study of 20 healthy male volunteers who were suddenly exposed to a hypobaric environment similar to that encountered within aeroplane cabins, markers of activated coagulation transiently Increased by two-fold to eight-fold. We suggest that hypobaric hypoxia, with sedentariness and dehydration, may cause this increased risk of venous thrombosis.

摘要

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