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微管细胞骨架的细胞周期调控

Cell cycle regulation of the microtubular cytoskeleton.

作者信息

Vantard M, Cowling R, Delichère C

机构信息

Laboratoire de Physiologie Cellulaire Végétale, URA 576, DBMS-CEA/Grenoble, France.

出版信息

Plant Mol Biol. 2000 Aug;43(5-6):691-703. doi: 10.1023/a:1006346107807.

Abstract

The microtubular element of the plant cytoskeleton undergoes dramatic architectural changes in the course of the cell cycle, specifically at the entry into and exit from mitosis. These changes underlie the acquisition of specialized properties and functions involved, for example, in the equal segregation of chromosomes and the correct positioning and formation of the new cell wall. Here we review some of the molecular mechanisms by which the dynamics and the organization of microtubules are regulated and suggest how these mechanisms may be under the control of cell cycle events.

摘要

植物细胞骨架的微管元件在细胞周期过程中会发生显著的结构变化,尤其是在有丝分裂的进入和退出阶段。这些变化是获得特殊性质和功能的基础,例如参与染色体的均等分离以及新细胞壁的正确定位和形成。在这里,我们综述了一些调节微管动力学和组织的分子机制,并提出这些机制可能如何受到细胞周期事件的控制。

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