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环状软骨上部分喉切除术后的喉狭窄

Laryngeal stenosis after supracricoid partial laryngectomy.

作者信息

Diaz E M, Laccourreye L, Veivers D, Garcia D, Brasnu D, Laccourreye O

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Laënnec Hospital, University of Paris V, France.

出版信息

Ann Otol Rhinol Laryngol. 2000 Nov;109(11):1077-81. doi: 10.1177/000348940010901115.

Abstract

The purpose of this study was to review the incidence, risks, management, and outcomes of nontumoral laryngeal stenosis after supracricoid partial laryngectomy (SCPL) in a case series of 376 consecutive SCPLs performed at 1 institution from 1975 to 1995 with a minimum of 3 years of follow-up. Post-SCPL nontumoral symptomatic laryngeal stenosis was defined as an inability to decannulate patients before the 60th postoperative day (group 1) or the development of dyspnea (in patients without local recurrence) after an initial period of prolonged, successful decannulation (group 2). Of 376 SCPLs performed, nontumoral symptomatic laryngeal stenosis developed in 14 (3.7%). There were 7 patients (1.85%) in group 1 and 7 patients (1.85%) in group 2. In univariate analysis, none of the following variables appeared to be statistically related to the risk of immediate stenosis (group 1): age, gender, comorbidity, diabetes mellitus, symptomatic gastroesophageal reflux, arteritis, preoperative radiotherapy, arytenoid cartilage disarticulation, type of reconstruction performed, and postoperative radiotherapy. A delayed laryngeal stenosis (group 2) was statistically more likely to occur if the reconstruction performed at the time of SCPL was a cricohyoidopexy (p = .01). Successful management of the laryngeal stenosis without permanent tracheostomy was achieved in 5 group 1 patients and 3 group 2 patients. We believe that stenosis in group I patients arose through technical error, whereas group 2 patients seemed to suffer from problems of healing, mainly cicatricial narrowing of the airway at the site of the cricohyoidal impaction, or pexis. As a result, whereas laryngeal stenosis in group 1 patients was usually more easily correctable through dilation, laser incision, or resection of redundant tissue or revision of the impaction, laryngeal stenosis in group 2 patients presented a more difficult and frustrating complication. The management and outcomes of these patients are presented.

摘要

本研究的目的是回顾在1975年至1995年间于1家机构连续进行的376例环状软骨上部分喉切除术(SCPL)病例系列中,非肿瘤性喉狭窄的发生率、风险、处理方法及预后情况,所有病例均进行了至少3年的随访。SCPL术后非肿瘤性有症状喉狭窄定义为:术后60天前患者无法拔管(第1组),或在最初一段长时间成功拔管后(无局部复发的患者)出现呼吸困难(第‌2组)。在376例实施的SCPL手术中,14例(3.7%)出现了非肿瘤性有症状喉狭窄。第1组有7例患者(1.85%),第2组有7例患者(1.85%)。单因素分析显示,以下变量均与即刻狭窄(第1组)风险无统计学关联:年龄、性别、合并症、糖尿病、有症状的胃食管反流、动脉炎、术前放疗、杓状软骨脱位、所进行的重建类型及术后放疗。如果SCPL时进行的重建为环状软骨舌骨固定术,则术后延迟性喉狭窄(第2组)在统计学上更易发生(p = 0.01)。5例第1组患者和3例第2组患者成功处理了喉狭窄且未行永久性气管造口术。我们认为第1组患者的狭窄是由技术失误导致的,而第2组患者似乎存在愈合问题,主要是环状软骨舌骨固定处气道瘢痕性狭窄。因此,第1组患者的喉狭窄通常通过扩张、激光切开、切除多余组织或调整固定术更容易纠正,而第2组患者的喉狭窄则是一种更棘手且令人沮丧的并发症。本文介绍了这些患者的处理方法及预后情况。

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