Fu Z, Kato H, Sugahara K, Kubo T
Laboratory of Nutritional Biochemistry, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan.
Biol Reprod. 2000 Dec;63(6):1795-800. doi: 10.1095/biolreprod63.6.1795.
The effects of retinoic acid on the development of reproductive organs and egg production in female Japanese quail (Coturnix coturnix japonica) were investigated. Female quail were fed a diet containing retinoic acid at 4 mg/kg (RA) or two diets containing retinyl acetate at 5000 IU/kg (VA1) or 14 000 IU/kg (VA2) after being fed a vitamin A-free diet for 2 wk (experiment 1). The oviduct and ovary grew more rapidly (P < 0.05) in RA-treated quail than in VA-treated quail at 5 wk of age. In addition, the body weight of RA-fed quail was also greater (P: < 0.05) than that of VA-fed quail at 5 wk. The RA-treated quail laid their first eggs approximately 5 days earlier (P < 0.05) than the VA-treated quail. Furthermore, these RA-fed quail laid more eggs (P < 0.05) than those VA-fed quail during the experimental period. To confirm the results of experiment 1, a similar experiment was conducted to record the first egg and total eggs laid by quail fed VA2 or RA (experiment 2). The early onset of oviposition was again observed in the RA-treated group (P < 0.01). These results suggest that retinoic acid has a stimulating effect on the reproductive system of female Japanese quail, as has been previously shown in the reproductive system of male Japanese quail.
研究了视黄酸对雌性日本鹌鹑（Coturnix coturnix japonica）生殖器官发育和产蛋的影响。在雌性鹌鹑饲喂不含维生素A的日粮2周后（实验1），分别给它们饲喂含4 mg/kg视黄酸的日粮（RA）或含5000 IU/kg（VA1）或14000 IU/kg（VA2）醋酸视黄酯的两种日粮。在第5周龄时，RA处理组鹌鹑的输卵管和卵巢生长速度比VA处理组鹌鹑更快（P<0.05）。此外，第5周时，RA饲喂组鹌鹑的体重也高于VA饲喂组鹌鹑（P<0.05）。RA处理组鹌鹑产第一枚蛋的时间比VA处理组鹌鹑早约5天（P<0.05）。此外，在实验期间，这些RA饲喂组鹌鹑产蛋量也多于VA饲喂组鹌鹑（P<0.05）。为了证实实验1的结果，进行了一项类似的实验，记录饲喂VA2或RA的鹌鹑产第一枚蛋的时间和总产蛋数（实验2）。在RA处理组中再次观察到产卵提前开始（P<0.01）。这些结果表明，视黄酸对雌性日本鹌鹑的生殖系统有刺激作用，正如先前在雄性日本鹌鹑的生殖系统中所显示的那样。
