Hikosaka M, Yuasa F, Yuyama R, Motohiro M, Mimura J, Kawamura A, Sumimoto T, Sugiura T, Iwasaka T
The Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan.
Am J Cardiol. 2000 Dec 1;86(11):1241-4, A6. doi: 10.1016/s0002-9149(00)01209-1.
We evaluated the effect of angiotensin-converting enzyme inhibition (quinapril) on cardiopulmonary baroreflex sensitivity in 30 patients with uncomplicated myocardial infarction (quinapril group, 15 patients; placebo group, 15 patients) at 5 and 10 days after the onset of myocardial infarction. This study indicates that quinapril improved cardiopulmonary baroreflex and thus reduced sympathetic outflow in patients with acute myocardial infarction.
我们评估了血管紧张素转换酶抑制剂(喹那普利)对30例无并发症心肌梗死患者(喹那普利组15例;安慰剂组15例)在心肌梗死后5天和10天时心肺压力反射敏感性的影响。本研究表明,喹那普利改善了急性心肌梗死患者的心肺压力反射,从而减少了交感神经传出活动。