Biondo S, Jaurrieta E, Martí Ragué J, Ramos E, Deiros M, Moreno P, Farran L
Department of Surgery, Ciudad Sanitaria y Universitaria de Bellvitge, University of Barcelona, Spain.
Br J Surg. 2000 Nov;87(11):1580-4. doi: 10.1046/j.1365-2168.2000.01556.x.
Classically a primary colonic anastomosis is not performed in the presence of left colonic peritonitis. Recently there has been a trend towards resection and anastomosis in selected patients, but no prospective study concerning the safety of this approach has been published. The objective of this study was to define the role of intraoperative colonic lavage with resection and primary anastomosis (RPA) in left colonic peritonitis, and to evaluate the differences in outcome in patients with diffuse or localized peritonitis.
Between January 1994 and December 1998, 127 patients underwent emergency operation for a distal large bowel perforation. RPA was the operation of choice and was performed in 61 patients, 38 with localized and 23 with diffuse peritonitis. Septic shock, faecal peritonitis, immunocompromised status and American society of Anesthesiologists grade IV were contraindications to the one-stage procedure. Alternative operations used in high-risk patients were Hartmann's procedure in 55 patients, subtotal colectomy in eight and colostomy in three.
There were two deaths (3 per cent) among 61 patients treated by RPA and one (2 per cent) case of clinical anastomotic dehiscence. Overall morbidity was 39 per cent and the overall mean(s.d.) hospital stay was 18(15) days. No statistical differences were observed between patients with localized and diffuse peritonitis treated by RPA.
RPA may be the operation of choice in selected patients with left colonic diffuse peritonitis.
传统上,存在左半结肠腹膜炎时不进行一期结肠吻合术。最近,在部分患者中出现了切除并吻合的趋势,但尚未发表关于这种方法安全性的前瞻性研究。本研究的目的是确定术中结肠灌洗联合切除及一期吻合术(RPA)在左半结肠腹膜炎中的作用,并评估弥漫性或局限性腹膜炎患者的预后差异。
1994年1月至1998年12月期间,127例患者因远端大肠穿孔接受急诊手术。RPA是首选手术,61例患者接受了该手术,其中38例为局限性腹膜炎,23例为弥漫性腹膜炎。感染性休克、粪性腹膜炎、免疫功能低下状态及美国麻醉医师协会分级IV级是一期手术的禁忌证。高危患者采用的替代手术包括55例行Hartmann手术、8例行次全结肠切除术、3例行结肠造口术。
61例接受RPA治疗的患者中有2例死亡(3%),1例(2%)临床吻合口裂开。总体发病率为39%,总体平均(标准差)住院时间为18(15)天。接受RPA治疗的局限性和弥漫性腹膜炎患者之间未观察到统计学差异。
对于部分左半结肠弥漫性腹膜炎患者,RPA可能是首选手术。