Rumelt S, Cohen I, Rehany U
Department of Ophthalmology, Western Galilee-Nahariya Medical Center, Nahariya, Israel.
Cornea. 2000 Nov;19(6):857-8. doi: 10.1097/00003226-200011000-00020.
To describe unilateral deep marginal corneal infiltrates and chronic anterior uveitis in a young patient with sinus histiocytosis and massive lymphadenopathy.
A 20-year-old man with a painless enlargement of his cervical lymph nodes was followed for five years after debulking of these nodes on the right side for right chronic anterior uveitis and deep marginal corneal infiltrates.
Histological sections of cervical lymph node confirmed the diagnosis of sinus histiocytosis with the typical emperipolesis. The uveitis partially responded to topical corticosteroid treatment but tended to recur upon its withdrawal. The marginal corneal infiltrates resolved gradually over a period of five years.
Marginal corneal infiltrates and uveitis may presumably be associated with sinus histiocytosis. Patients with sinus histiocytosis should also be screened for rare ocular involvement, such as uveitis and corneal infiltrates.
描述一名患有窦性组织细胞增多症和巨大淋巴结病的年轻患者的单侧深层角膜边缘浸润和慢性前葡萄膜炎。
一名20岁男性，右侧颈部淋巴结无痛性肿大，因右侧慢性前葡萄膜炎和深层角膜边缘浸润进行淋巴结减容术后随访5年。
颈部淋巴结组织切片确诊为窦性组织细胞增多症，具有典型的血细胞吞噬现象。葡萄膜炎对局部糖皮质激素治疗部分有效，但停药后易复发。角膜边缘浸润在5年内逐渐消退。
角膜边缘浸润和葡萄膜炎可能与窦性组织细胞增多症有关。窦性组织细胞增多症患者也应筛查罕见的眼部受累情况，如葡萄膜炎和角膜浸润。
