Green R M, DeWeese J A, Rob C G
Surgery. 1975 Jan;77(1):24-33.
Arterial emboli were extracted from 79 patients between 1955 and 1963 with polyethylene catheter suction systems and/or retrograde flushing and from 149 patients between 1963 and 1973 with Fogarty catheters. The Fogarty-era patients were older, had a greater incidence of ischemic heart disease, and presented with a greater degree of preoperative peripheral ischemia. The limb salvage rate of 87 percent after Fogarty catheter embolectomy was not statistically different from the salvage rate of 79 percent after suction catheter embolectomy, but the number of limbs with distal pulses postoperatively was significantly greater after Fogarty treatment, 64 vs. 42 percent. Delay in treatment and the presence of prior occlusive vascular disease adversely affected results in both eras. The in-hospital embolic recurrences occurred in 9 percent of the patients anticoagulated postoperatively and in 31 percent of those not anticoagulated. Heparin and warfarin were equally effective in preventing recurrences, but wound complications were seen in 33 percent of the heparinized patients, compared with 7 percent of those receiving warfarin and 4 percent of those not anticoagulated.
1955年至1963年间,使用聚乙烯导管抽吸系统和/或逆行冲洗法从79例患者中取出动脉栓子;1963年至1973年间,从149例患者中使用Fogarty导管取出动脉栓子。Fogarty导管时代的患者年龄更大,缺血性心脏病发病率更高,术前外周缺血程度更严重。Fogarty导管取栓术后肢体挽救率为87%,与抽吸导管取栓术后79%的挽救率相比,差异无统计学意义,但Fogarty治疗后术后有远端脉搏的肢体数量显著更多,分别为64%和42%。治疗延迟和既往存在闭塞性血管疾病在两个时代均对治疗结果产生不利影响。术后接受抗凝治疗的患者中,9%发生院内栓塞复发;未接受抗凝治疗的患者中,31%发生院内栓塞复发。肝素和华法林在预防复发方面同样有效,但肝素化患者中有33%出现伤口并发症,而接受华法林治疗的患者中这一比例为7%,未接受抗凝治疗的患者中这一比例为4%。