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猪卡氏肺孢子虫感染的免疫组织化学研究:卡氏肺孢子虫肺炎的评估及回顾性调查

Immunohistochemical study of Pneumocystis carinii infection in pigs: evaluation of Pneumocystis pneumonia and a retrospective investigation.

作者信息

Kondo H, Hikita M, Ito M, Kadota K

机构信息

Livestock Hygiene Service Center, Sapporo, Hokkaido, Japan.

出版信息

Vet Rec. 2000 Nov 4;147(19):544-9. doi: 10.1136/vr.147.19.544.

DOI:10.1136/vr.147.19.544
PMID:11095394
Abstract

Infection with Pneumocystis carinii was demonstrated immunohistochemically in the lungs of pigs 15 to 75 days of age from a herd with epidemic pneumonia due to the organism. The distribution of the organism was centered on the airways, and extended progressively with age from the alveolar ducts to the alveoli. In a retrospective immunohistochemical study of 245 newborn to adult pigs which were necropsied between 1988 and 1995, P carinii infection was found in 87 pigs (35.5 per cent) aged between 17 days to seven months. In the pigs aged between one and three months the infection rate was 63.1 per cent. Pigs from herds in which suckler and weaner pigs shared the same air space were more heavily infected than those from the herds in which they were reared separately. There were no regional or seasonal variations in the level of infection, and the infection was not associated with any single disease.

摘要

在一群因卡氏肺孢子虫而发生流行性肺炎的猪群中,对15至75日龄仔猪的肺组织进行免疫组织化学检测,证实存在卡氏肺孢子虫感染。该病原体的分布以气道为中心,并随年龄增长从肺泡管逐渐扩展至肺泡。在一项对1988年至1995年间剖检的245头新生至成年猪的回顾性免疫组织化学研究中,在87头(35.5%)17日龄至7个月龄的猪中发现了卡氏肺孢子虫感染。在1至3月龄的猪中,感染率为63.1%。哺乳仔猪和断奶仔猪共用同一空间的猪群中的猪比分开饲养的猪群中的猪感染更严重。感染水平没有地区或季节差异,且该感染与任何单一疾病均无关联。

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