一名获得性免疫缺陷综合征患者接受白细胞介素-2治疗后出现结节病。
Sarcoidosis in a patient with acquired immunodeficiency syndrome treated with interleukin-2.
作者信息
Blanche P, Gombert B, Rollot F, Salmon D, Sicard D
机构信息
Service of Internal Medicine, René Descartes University, Cochin Hospital, Paris, France.
出版信息
Clin Infect Dis. 2000 Dec;31(6):1493-4. doi: 10.1086/317475.
Concomitant human immunodeficiency virus (HIV) infection and sarcoidosis is rare. Sarcoidlike reactions could belong to the "highly active antiretroviral therapy (HAART)-induced immune restitution syndrome." We report a case of sarcoidosis beginning after 2 months of interleukin-2 (IL-2) therapy in a patient with HIV who had undetectable plasmatic viral load under HAART and we discuss possible mechanisms.
人类免疫缺陷病毒（HIV）感染与结节病同时存在的情况较为罕见。类结节样反应可能属于“高效抗逆转录病毒治疗（HAART）诱导的免疫重建综合征”。我们报告了1例在接受HAART治疗且血浆病毒载量检测不到的HIV患者中，白细胞介素-2（IL-2）治疗2个月后出现结节病的病例，并讨论了可能的机制。
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