Fitchett D H, McNicol M W, Riordan J F
Br Med J. 1975 Jan 11;1(5949):53-5. doi: 10.1136/bmj.1.5949.53.
After the administration of intravenous salbutamol (100-300 mug) to 11 patients admitted to hospital with a severe exacerbation of asthma there was a mean increase in peak expiratory flow of 44% accompanied by a rise in pulse rate of 24 beats/min. Blood gas tensions showed a trend to improvement and there were no serious side effects. It is concluded that intravenous salbutamol is an effective and apparently safe bronchodilator in the management of acutely ill patients with severe asthma.
对11名因哮喘严重发作而住院的患者静脉注射沙丁胺醇(100 - 300微克)后,呼气峰值流速平均增加44%,同时脉搏率上升24次/分钟。血气张力呈改善趋势,且无严重副作用。结论是,静脉注射沙丁胺醇在治疗重症急性哮喘患者时是一种有效且明显安全的支气管扩张剂。