沙丁胺醇与异丙肾上腺素对支气管哮喘患者肺量测定及血气张力影响的比较
Comparison of effect of salbutamol and isoprenaline on spirometry and blood-gas tensions in bronchial asthma.
作者信息
Palmer K N, Legge J S, Hamilton W F, Diament M L
出版信息
Br Med J. 1970 Apr 4;2(5700):23-4. doi: 10.1136/bmj.2.5700.23.
Abstract
The effect of the aerosol inhalation of 200 mug. of salbutamol and 1,000 mug. of isoprenaline on spirometry and blood-gas tensions was compared in the same 11 asthmatic subjects. Both drugs significantly reduced airway obstruction, and the extent of the reduction did not differ for periods of up to 30 minutes. After isoprenaline tachycardia and a small significant fall in arterial oxygen tension occurred, whereas after salbutamol there was no change in pulse rate and the arterial oxygen tension did not fall.
摘要
在11名相同的哮喘患者中比较了雾化吸入200微克沙丁胺醇和1000微克异丙肾上腺素对肺量计和血气张力的影响。两种药物均显著减轻气道阻塞，在长达30分钟的时间段内，减轻程度没有差异。吸入异丙肾上腺素后出现心动过速且动脉血氧张力有小幅显著下降，而吸入沙丁胺醇后脉搏率没有变化且动脉血氧张力未下降。
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