Grabe H J, Meyer C, Hapke U, Rumpf H J, Freyberger H J, Dilling H, John U
Department of Psychiatry and Psychotherapy, Ernst-Moritz-Arndt-Universität Greifswald, Klinikum der Hansestadt Stralsund, Germany.
Eur Arch Psychiatry Clin Neurosci. 2000;250(5):262-8. doi: 10.1007/s004060070017.
Despite the worldwide relevance of obsessive-compulsive disorder (OCD) there are considerable differences in prevalence rates and gender ratios between the studies and a substantial lack of prevalence data on subclinical OCD. Moreover, data on quality of life and on psychosocial function of subjects with OCD and subclinical OCD in the general population are missing to date.
German versions of the DSM-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 4075 persons aged 18-64 years living in a northern German region. Specific DSM-IV based criteria for subclinical OCD were used.
The life-time prevalence rates for OCD and subclinical OCD were 0.5% and 2%, respectively. Twelve month prevalence rates were 0.39% and 1.6%, respectively. The gender female:male ratio was 5.7 in OCD and 1.2 in subclinical OCD. In various measures of psychosocial function and quality of life, OCD and subclinical OCD were significantly impaired. However, subclinical OCD subjects did not visit mental health professionals more often than controls.
Due to different epidemiological characteristics subclinical OCD might represent a syndrome distinct from OCD which is also associated with significant impairments in personal and interpersonal functions and in quality of life.
尽管强迫症（OCD）在全球范围内都具有相关性，但不同研究之间的患病率和性别比例存在显著差异，并且亚临床强迫症的患病率数据严重缺乏。此外，迄今为止，普通人群中强迫症和亚临床强迫症患者的生活质量和心理社会功能数据也缺失。
对居住在德国北部地区的4075名年龄在18 - 64岁的代表性样本进行了经DSM - IV改编的复合国际诊断访谈的德语版本调查。使用了基于DSM - IV的亚临床强迫症特定标准。
强迫症和亚临床强迫症的终生患病率分别为0.5%和2%。十二个月患病率分别为0.39%和1.6%。强迫症的女性与男性性别比为5.7，亚临床强迫症为1.2。在心理社会功能和生活质量的各项指标中，强迫症和亚临床强迫症均有显著损害。然而，亚临床强迫症患者就诊心理健康专业人员的频率并不比对照组更高。
由于不同的流行病学特征，亚临床强迫症可能代表一种与强迫症不同的综合征，它也与个人和人际功能以及生活质量的显著损害有关。
