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一名因肿瘤转移至脊髓导致截瘫的患者剖宫产手术的麻醉

Anesthesia for Cesarean section in a patient with paraplegia resulting from tumour metastases to spinal cord.

作者信息

Jones B P, Milliken B C, Penning D H

机构信息

Department of Anesthesia, Tripler Army Medical Center, Hawaii 96859-5000, USA.

出版信息

Can J Anaesth. 2000 Nov;47(11):1122-8. doi: 10.1007/BF03027967.

Abstract

PURPOSE

Spinal cord injured patients present multiple unique challenges to the anesthesiologist. These include choice of muscle relaxant and management of autonomic hyperreflexia. We report the anesthetic management for Cesarean delivery in a patient who was paraplegic due to spinal canal metastases. Preeclampsia and fever complicated this case.

CLINICAL FEATURES

The patient presented at 29 wk gestation with progressive paraplegia at the T10 level due to metastatic osteosarcoma. She had a decompressive laminectomy without improvement in her paralysis. She subsequently developed preeclampsia at 31 wk gestation, and underwent Cesarean delivery for breech presentation under general anesthesia. Anatomical concerns left us unsure of the efficacy or safety of neuraxial anesthesia.

CONCLUSIONS

Preeclampsia and autonomic hyperreflexia are generally indications for regional anesthesia for Cesarean section. Tumour in her spinal canal and laboratory abnormalities including thrombocytopenia and a potential urosepsis dissuaded us from this option. Additionally, rapid sequence induction and intubation were not preferred due to paraplegia, leading us to secure the airway fibreoptically.

摘要

目的

脊髓损伤患者给麻醉医生带来了诸多独特的挑战。这些挑战包括肌肉松弛剂的选择以及自主神经反射亢进的处理。我们报告了一例因椎管转移瘤导致截瘫的患者剖宫产手术的麻醉管理情况。该病例并发了子痫前期和发热。

临床特征

患者孕29周时因转移性骨肉瘤出现T10水平进行性截瘫。她接受了减压性椎板切除术,但瘫痪症状并未改善。随后,她在孕31周时并发子痫前期,并在全身麻醉下因臀位行剖宫产手术。解剖学方面的问题使我们对神经轴麻醉的有效性和安全性存疑。

结论

子痫前期和自主神经反射亢进通常是剖宫产区域麻醉的指征。她椎管内的肿瘤以及包括血小板减少和潜在泌尿道感染在内的实验室异常情况使我们放弃了这一选择。此外,由于截瘫,快速顺序诱导插管并非首选,这导致我们通过纤维支气管镜确保气道安全。

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